Job Postings
ChemoCentryx, a pharmaceutical company located in Mountain View, CA, seeks highly motivated professionals to join our team.
All ChemoCentryx employees share the rewards of their work through a generous stock option program. We also offer 401K and Flexible Spending Accounts, and a comprehensive benefits package, including medical, dental and vision coverage and life and long-term disability insurance.
Please email your resume & cover letter to: hiring@chemocentryx.com or FAX to: (650) 210-2910. No phone calls please. EOE
Associate Director – Chemistry
In this position, you will make significant contributions to understanding complex scientific issues and solving difficult scientific problems that have eluded others in the field. You will also provide scientific leadership in determining the direction of research projects, seeking out opportunities to break new ground that will distinguish the company, interacting with senior management to help shape the company’s scientific strategy.
Candidates should be an acknowledged expert in the field of medicinal chemistry, with demonstrated success in leading drug discovery projects, supervising scientific staff, and advancing high quality small molecule candidates into preclinical development. Excellent communication skills and the ability to thrive in an interdisciplinary environment are essential. The qualified candidate will have a Ph.D. and postdoctoral experience in synthetic organic chemistry, with a minimum of 8+ years of medicinal chemistry experience in the pharmaceutical industry covering all stages of the drug discovery process.
Reference Job Code: CCX#65
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Research Assistant/Associate - Biology
ChemoCentryx is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing orally-administered small molecule therapeutics that target the chemokine and chemo-attractant systems in order to treat autoimmune diseases, inflammatory disorders and cancer.
As a member of the lead discovery and optimization group, your primary responsibility will be to develop high-quality antagonist that advance into preclinical development by providing high-quality biological data using a combination of in vitro biochemical and cell culture assays, including cell migration, radioligand binding and cytoplasmic calcium flux assays. Speed, quality and communication are essential skills for this position. In addition, handling and tracking novel compounds, growing mammalian cells in sterile tissue culture, handling laboratory robotics, maintaining accurate and complete records in a laboratory notebook, and being responsible for entering results into an Oracle database are required.
Basic requirements include a BS in biological sciences with a strong GPA. Preferred qualifications include a MS and/or 2 to 5 years experience in pharmacology or drug optimization.
Reference Job Code: CCX#59
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Research Assistant/Associate - Chemistry
We seek a highly motivated professional responsible for the design and synthesis of drug candidates for lead optimization within the medicinal chemistry research group. The successful candidate will have demonstrated expertise in multi-step organic synthesis and structural characterization.
This position requires:
- Valid permission to work in the U.S.
- Requires a BS or MS degree in chemistry.
- Hands-on experience using modern chromatographic and spectroscopic techniques such as NMR, MS and HPLC.
- Two to eight years of experience in medicinal or synthetic organic chemistry.
- Industrial experience within a medicinal chemistry environment is preferred.
Reference Job Code: CCX#57
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Scientist I / II – DMPK / Bioanalytical
This position will be involved in clinical PK sample bioanalysis and/or discovery ADME/DMPK support. The candidate will be responsible for experimental design, performing the experiments, data analysis / interpretation, and producing study reports. Depending on the level of experience, the successful candidate may also serve as the DMPK project representative on drug discovery project teams and work closely with medicinal chemists to identify and solve the DMPK issues for the SAR molecules, or contribute to the clinical PK analysis function.
The successful candidate needs to have a Ph.D. or M.Sc. degree in chemistry, biochemistry, drug metabolism, pharmacokinetics or a related field, extraordinary strength in bioanalytical skills, and good understanding of pharmacokinetics in the context of drug discovery and development. The candidate should also have relevant bioanalytical experience in GLP or GLP-like settings, following the necessary SOPs and performing bioanalytical method validation based on the FDA guidance. Experience in performing ADME assays such as metabolic stability, CYP450 inhibition and protein binding is also important. The candidate needs to have excellent oral communication and report writing skills and work as a highly effective team member. Industrial experience of 1-5 years for a Ph.D. and 5-10 years for a M.Sc. is preferred.
Reference Job Code: CCX#71
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Scientist II/Senior Scientist - Biology
We currently seek a Scientist II/Senior Scientist to join our Biology Group. The position requires a Ph.D. in Immunology, or related field, with experience in project leadership and the use of established animal models of human disease.
The successful candidate will have the following primary responsibilities:
- Lead at least one project to identify and select novel chemokine/chemoattractant receptor therapeutics for the treatment of disease.
- Design experiments to determine the efficacy and mechanism of action of candidate molecules using established mouse models.
- Help in the development and implementation of new animal models of diseases.
- Interface with project members in order to adhere to project goals and timelines.
- Provide presentations to articulate research results, milestones, challenges, and plans
Requirements
- The successful candidates will have a PhD in Immunology, or related field, and 3-5 years industry experience in biopharmaceutical drug discovery.
- Extensive experience with mouse-based models of disease, preferably autoimmune diseases.
- Experience in multi-color flow cytometry is a must.
- Experience in immunohistochemistry and tissue culture is desired.
- Previous experience of working with human cells is a plus.
- Excellent verbal, written and problem solving skills are required. The ability to work as part of a cross-functional team and outstanding communication and presentation skills are required.
- The successful candidate will enjoy working as a member of a fast-paced multidisciplinary team in an entrepreneurial environment.
Reference Job Code: CCX#76
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